The Togo striker gets the nod following his impressive performance against Chelsea as Spurs look to move above Arsenal into fourth place on the Potters' 150th anniversary
Compared with the starting XI against Chelsea in midweek, Steven Caulker and Clint Dempsey come in for Benoit Assou-Ekotto and Lewis Holtby, respectively.
For Stoke, Matthew Etherington starts in place of Cameron Jerome in an otherwise unchanged team from the eleven who drew with Sunderland last Monday, meaning Etherington as well as striker Peter Crouch will be facing their former club.
Stoke are celebrating their 150th anniversary, but for Spurs it is a massive game in their quest for Champions League qualification. If Andre Villas-Boas' team can take all three points from the Potteries they will leapfrog rivals Arsenal into fourth place ahead of the Gunners' own must-win clash with FA Cup winners Wigan on Tuesday.
Stoke: Begovic; Shotton, Shawcross, Huth, Wilson; Adam, Whitehead, Nzonzi, Etherington; Walters, Crouch.
Subs: Sorensen, Cameron, Jones, Owen, Kightly, Wilkinson, Jerome.
Tottenham: Lloris; Walker, Caulker, Dawson, Vertonghen; Lennon, Huddlestone, Parker, Dempsey; Adebayor, Bale.
Subs: Friedel, Naughton, Carroll, Dembele, Holtby, Sigurdsson, Defoe.