The 20-year-old, who joined Alan Pardew's side from Nancy in January, had replaced the injured Mathieu Debuchy during the first half of the Magpies' defeat at the DW Stadium on Sunday but was the recipient of the knee-high challenge less than 10 minutes after coming on.
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"It was an awful tackle. I have got a boy going to hospital and that's a worse feeling than losing," Pardew told the BBC after the game.
"It looks like knee ligaments and he's got terrible bruising on his leg as well. It looked a bad challenge but I didn't realise how bad until it filtered through to us from the sideline."
Despite the severity of the challenge, Wigan chairman Dave Whelan claims that McManaman won the ball "as clean as a whistle".
"The ball was there and McManaman went in for the ball and got the ball, as clean as a whistle, then followed through and they collided," Whelan told BBC Radio 5 Live.
“He hasn't gone over the ball. That's an accident.”