It has been nearly 10 years since the Andalusians beat Barca in a league game away from home, and Bet Victor price a home win at 1/5 (1.20).
Sevilla, meanwhile, are without a win on the road since September having lost seven of their last nine away games and can be backed to change that record at 14/1 (15.00) by winning in Catalunya.
Yet there is little reason to think this will be anything other than a routine win for the Catalans, despite their recent humbling by Milan.
The perennial issue then of attempting to find value when backing Barca at home once more rears its head for punters and there are few markets which may be of interest.
What looks like offering the best value is backing both teams to score at 7/10 (1.70) which on paper is a decent option despite Sevilla's poor record away from home.
Barcelona have conceded in each of their last 10 matches in all competitions, with their defence being less than solid throughout the season.
Sevilla for their part while not managing to win any away games recently, have been scoring on their travels, netting in four of their last five away games, so they should test the home side's resolve.
They also managed to score twice against Barca earlier on this season, and this bet seems to offer the best value for punters wishing to invest in the match.
With five goals in his last six games Sevilla striker Alvaro Negredo is in decent form, and appears to offer punters searching for a value bet a decent option priced as he is at 10/3 (4.33) to net at any time.
|Both teams to score at 7/10 (1.70) BetVictor
||Alvaro Negredo to score at any time at 10/3 (4.33) with BetVictor|
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Phil Kitromilides is a sports anchor working on TV in Madrid. You can also follow Phil on Twitter.