Diego Simeone's side are two pints adrift of second-placed Barcelona and three behind leaders Real Madrid going into the weekend
Atletico Madrid have fallen to the bottom of the pile in the three-way chase for La Liga title but will want to keep pace by beating Celta Vigo.
Diego Simeone's men sit third in the Spanish top flight, two points adrift of second-placed Barcelona and three points behind city rivals and leaders Real Madrid.
However, Atletico's title charge has waned in recent weeks as they have picked up just one win from their last four league fixtures, while they also conceded a late equaliser to miss out on victory against Real on Sunday.
Saturday's trip to Vigo marks the beginning of a series of very winnable fixtures for the men from the Spanish capital, who face Espanyol, Real Betis and Granada before the end of March.
Atleti picked up a 2-1 win when the sides met in Madrid in October and are unbeaten in the last five meetings between the two.
Atleti are without full-back Javier Manquillo (neck), who has taken his first steps towards making a return to training, while defender Rafinha (toe) is a doubt for the hosts and forward Mario Bermejo (thigh) could be back in contention.