While Kevin-Prince was born in Germany, he opted to represent the Black Stars at national team level but his brother Jerome plays for die Mannschaft and they will line up against each other this weekend.
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"It’s not the first time [at international level] he’s played against his brother, he had that experience four years ago," Ayew told the media. "And he plays for Schalke, so he plays against him for Bayern, so it won’t distract him at all.
"When I play my brother, it’s something fantastic. It’s not often that players get the opportunity to play against each other at this level."
Ayew does not feel his team need to alter their style for this encounter, explaining that aside from the start and end of the USA match, which they lost 2-1, they played a good game.
"Ghana is just going to be Ghana," he stated. "The Germans are talking about our physicality, but we know we are also technical. We have a lot of qualities.
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"In 2006, we lost the first game and went through. In 2010, we won the first game and went through with four points.
"No one put us under this pressure; we put ourselves under this pressure so we need to get through strongly.
"We are ready to go out and die for our nation – we’re going to do everything to make our people proud."
The Marseille player’s father was nicknamed after Brazil legend Pele, but Ayew was keen to stress that the host nation of the World Cup has not yet produced any fond memories for him.
“This is my first time in Brazil and it has not given me anything – it could give me qualification to the next stage!”