Elsewhere, Bristol City, Ipswich and Peterborough all look for a win to aid their fight against relegation, and Middlesbrough can go second with victory over Birmingham
|WEEKEND FIXTURES IN FULL
With matchday 20 fast approaching in the Championship, Goal.com previews all the action in the second tier of English football.
Cardiff City have an opportunity to extend their one-point lead at the top of the table over Crystal Palace on Sunday, as the Welsh side host relegation candidates Sheffield Wednesday. Dave Jones' men, who were promoted from League One last season, sit second from bottom.
Meanwhile, Ian Holloway's Crystal Palace face a tough test at home against Brighton on Saturday, but a victory will see them leapfrog their promotion rivals for at least 24 hours.
Birmingham City host Middlesbrough in the weekend’s first action on Friday evening, with the away side able go level on points with Cardiff with three points. Lee Clarke’s side, however, will be keen to put distance between themselves and the relegation zone.
Leeds United travel to Huddersfield Town on Saturday lunchtime with a chance to go, at least temporarily, eighth and boost their play-off hopes.
Two of the Championship’s more disappointing sides, Bolton and Ipswich Town, face off at the Reebok Stadium, both in desperate need for a win. Ipswich currently sit 21st, with just two points separating themselves from a place in the bottom two while Bolton – who were a Premier League team just seven months ago – are in 17th place.
It's a similar tale for Wolves and Bristol City – who lie 18th and 22nd respectively – but a win for Derek McInnes' side could lift them out of the relegation places.
Millwall can go level on points with third-placed Middlesbrough if they manage to beat visiting Charlton, who can boost their own play-off hopes with a win.
A clash between two sides also battling out for promotion, Nottingham Forest and Hull City, takes place at the City Ground, with the Tigers already occupying sixth place and Forest just three points off in ninth.
Peterborough sit bottom of the Championship having picked up just one point from their last six matches and Darren Ferguson's side entertain Blackpool on Saturday.
Barnsley could find themselves sucked into the relegation zone on Saturday evening if results do not go their way, and they face a tricky trip to Watford, who are unbeaten in their last six matches.
Burnley and Blackburn face off on Sunday lunchtime in the Lancashire derby and Henning Berg's side will be looking to end their run of two straight defeats.