The 70-year-old is hoping the pair can continue to strike a chord after they combined for both goals in United's 2-1 win over Cluj and insists his side's strength is in attack
The 70-year-old saw his team narrowly overcome the tough Romanian outfit, with Pantelis Kapetanos putting the hosts ahead with a shock early goal.
However, United regained their composure, with Rooney assisting Van Persie twice to ensure United left Transylvania with all three points an Sir Alex hopes the successes will continue for the pair.
"The strength of the squad is in the attacking positions," he told ITV.
"The pass and the finish [for the second goal], both were equally as good. It's a fantastic finish but what a nice ball Wayne has dropped - I thought it was too far, but Robin has done well to get to it.
"It's difficult to say [if this is a partnership]. I hope so. I think there's combinations between a few of our players."
The Scot also complemented Cluj on their attitude throughout the match, and insists that despite a nervy encounter, any victory away in Europe is always a good result.
"If you see the way they kept going until the end, they put a lot of telling crosses into the box which kept us under pressure, kept us on edge," Sir Alex said.
"I've got to be pleased with the possession, the concentration was really good tonight.
"Apart from the goal, we've defended really well tonight, David [de Gea] made a good save towards the end, so I've got to be pleased. Coming away from home in Europe is never easy, and they've a good home record here."