Following the sacking of David Moyes on Tuesday, Giggs has been placed in temporary charge of the first team while Butt and Paul Scholes are assisting the 40-year-old with Phil Neville retained as part of the coaching staff.
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"It will be massive for us, a proud moment for us all," Butt told MUTV.
"To be there together is a bit of a surreal thing. We walked in here together when we were 12 and to be here now - I'm not 40 yet but Giggsy is, and myself and Scholes are nearly there too. So for us and Phil to be there together is a very proud moment.
"We're here to try to help the club and get the results that we want from now until the end of the season. What happens after that, who knows?"
Despite the fact United will register their worst ever finish in the Premier League era this season, Butt insists the club possess "hard-working" players and the former midfielder has challenged the squad to recover from last Sunday's 2-0 defeat to Everton.
"We've got some amazing players at this club, good lads who care about the club, who are really positive about United and want the best for the club,” said Butt.
"Saturday is a massive occasion, not only for Ryan, but for the staff, the fans and the players as well because they know that we've underachieved as a club this year.
"The players in that changing room know how good they are. They look round, look left and look right at the players next to them and know that they are very proud, hard-working lads. I'm sure we'll see that on Saturday."