The two sides go into the game level on points with David Moyes's men and having ended a 26-year wait for victory at Old Trafford last season with a 3-2 win.
|8/1||Roberto Soldado is 8/1 with Coral to score the first goal in Manchester United v Spurs|
"I'm really looking forward to it," he told the club's official website.
"We played at United in the Champions League when I was at Valencia; we drew 1-1.
"It's a very big game. We're on the same points as United and, if we attack them, we have a chance to beat them."
The Spain international also took time out to praise fellow striker Emmanuel Adebayor, who has been in fine form since being recalled to the first team under Sherwood.
"I've a great partnership with Adebayor, we're playing close to each other and we're causing teams problems," he enthused. "I think we'll get better in the future as well."