The Urugyuan provided the assist for Clyne's goal during Saints' 4-1 rout of Aston Villa, a win which ended a difficult run of results for Nigel Adkins side.
The young defender believes Ramirez's creativity will be a major asset to the south coast club this season, and insisted they are lucky to have him.
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"Gaston is fantastic – he's a great player with lots of creativity," he told Southampton's official website.
"He has the ability to find players, so I made a nice little run and he put me in so all I had to do was finish it.
"You could pass the ball to him with a player on his back and he'd still deal with it, and If you make a run forward then he'll always find you because he's got that quality.
"It's always good to have a player like him on your side, and we're lucky to have him."
Clyne also expressed delight at helping his side to their first win of the season and hailed manager Nigel Adkins as the reason he was able to get on the scoresheet.
"I'm delighted with the goal," said Clyne.
"The gaffer told me to bomb forward so I did that to try and help my team both in attack and defence.
"I just found myself forward and it was a lovely ball from Ramirez to play me in and score. We won the game as well, so I couldn't be happier."