Real Madrid, priced at 13/10 (2.30) to win, are four points above Barcelona and in pole position for Carlo Ancelotti to lead them to the title if they can get a positive result from Sunday's match but Atletico Madrid are also lying in wait for any potential slip up from Los Blancos. The Catalan giants are 2/1 (3.0) shots to stun the hosts with a win and the draw trades at 5/2 (3.50).
With such a highly anticipated clash on the horizon Paddy Power are offering new customers the chance to choose their enhanced price involving the two biggest names in Spanish football.
Cristinao Ronaldo, best priced 19/20 (1.95) to score anytime has been enhanced to 4/1 (5.0) by the Irish bookmaker.
That's a huge price for a man who has 25 goals in 24 La Liga games and has found the net with alarming regularity in recent Clasico matches, netting five times in the last six games between the two clubs.
If Barcelona are to have a chance of collecting three La Liga points from the Bernabeu for the first time since December 2011 then you'd imagine Lionel Messi would have to feature pretty heavily. The Argentina international has had his injury problems this season but his goalscoring record speaks for itself, 18 league goals in 21 games justifies why he's a best priced 11/10 (2.10) to score anytime on Sunday.
That is, unless you're a new Paddy Power customer, in which case you can snap up the 5/1 (6.0) about the 26-year-old forward getting on the scoresheet for his side.
These prices are a fantastic opportunity for anyone without a Paddy Power account to get their account off to a profitable start and the choice between the two superstars allows new players to select which price they believe offers the best value.
It's not just new customers that will be rewarded though; existing Paddy Power customers will be in for a refund on selected markets if Messi finds the net.
Losing first/last goalscorer, correct score and scorecast bets will be refunded by the bookmaker if Messi - who comes into this match fresh from a hat-trick against Osasuna last weekend - makes it 19 La Liga goals for the season.
|Messi OR Ronaldo?
|Ronaldo to score anytime at 4/1 with Paddy Power
||Messi to score anytime at 4/1 with Paddy Power|
Jim Knight is Chief Betting Editor at Goal and has been tipping football games since he was old enough to place a bet. He is a Leicester City fan, writer and member of the We Are Going Up Podcast