The Manchester United striker is expected to captain his country against Estonia and Andorra, while the Chelsea youngster, Michel Vorm and Ron Vlaar are also included
Aston Villa captain Ron Vlaar, Swansea goalkeeper Michel Vorm and Norwich striker Ricky van Wolfswinkel complete the Premier League Oranje contingent.
But Galatasaray playmaker Wesley Sneijder has once again been omitted, having previously been stripped of the captain's armband for Oranje's Asian tour earlier this summer.
Other notable absentees are Fulham goalkeeper Maarten Stekelenburg and Everton defender John Heitinga, while Tim Krul, Kevin Strootman, Klaas-Jan Huntelaar and Daryl Janmaat have been left out due to fitness issues.
Manchester City defender Karim Rekik, currently on loan at PSV, has been called up for the first time, while Jeffrey Bruma returns after a lengthy absence.
Augsburg defender Paul Verhaegh has also made the cut again after making his debut in the draw with Portugal earlier this month.
Netherlands currently sit top of Group D with 18 points from six games, holding a seven-point lead over second-placed Hungary.
|Ron Vlaar||Aston Villa|
|Bruno Martins Indi||Feyenoord|
|Stefan de Vrij||Feyenoord|
|Ricardo van Rhijn||Ajax|
|Marco van Ginkel||Chelsea|
|Rafael van der Vaart||Hamburg|
|Jeremain Lens||Dynamo Kiev|
|Robin van Persie||Manchester United|
|Arjen Robben||Bayern Munich|
|Ricky van Wolfswinkel||Norwich|