The ex-France coach believes his doubts about the Real Madrid striker have now been vidicated after his poor showing against Georgia
The former Olympique Lyonnais man has not scored for his country in 929 minutes of football and was roundly booed by Bleus fans after refusing to sing the Marseillaise before the match.
And Domenech feels Franck Ribery was also a disappointment, but was impressed with the performances of Blaise Matuidi and Mathieu Valbuena.
"I had already said it: Benzema confirms his uselessness and Ribery is still inconsistent. But that was before!" he wrote on Twitter.
"Valbuena and Matuidi are certain to face Spain. Ribery will also play Spain."
However, Benzema's striker partner, Olivier Giroud has defended Benzema's performance against the Georgians.
"He created chances. I was trying to set him up too. I was trying to find it. It's a partnership that could work and we achieved a lot tonight. There are no problems."
During Domenech's six-year tenure in charge of France, he had many well-publicised rows with players, most notably Nicolas Anelka at the 2010 World Cup.