The Sounders love this competition, having won the trophy for the last three years in a row, while their opponents Chivas are vying for a place in the final for the first time in their short history.
If the Rojiblancos are to make the last two, then they must defeat a side that they have not beaten in over three years, and have never beaten away from home.
It is no surprise then, that Robin Fraser's side are a lengthy 63/20 (4.15) with Panbet to make history and come out on top in this game.
Considering the home side's love affair with the cup, they must be worth backing at 9/10 (1.90) to win against a side who have barely troubled them in the past on their own turf.
Chivas would surely be happy to recreate their performance in the last trip to CenturyLink Field, when they held the hosts to a draw back in August.
You can get odds of 49/20 (3.45) on the two teams cancelling each other out again on Wednesday, although the Sounders will be desperate to avoid a draw and the lottery of penalties.
Sigi Schmid's boys are bound to come out all guns blazing in order to ensure progress to a fourth consecutive final, meaning Chivas may have to withstand a heavy barrage on their goalmouth.
Seattle's strikeforce was too much for their previous cup opponents, as they banged in 11 goals in the three rounds leading up to this stage.
With firepower like this on display, odds of 23/20 (2.15) seem extremely inviting on over 2.5 goals being scored in this game.
|Seattle Sounders to win at 9/10 (1.90) with PanBet
Over 2.5 goals at 23/20 (2.15) with PanBet
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Al Hain-Cole is a Liverpool fan, experienced tipster and avid follower of European football. He specialises in accumulators and if you would like to read more from Al you can follow him on Twitter here.
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