The Spanish goalkeeper was dismissed in the second half of the clash at St Mary's and will now be suspended for the clash with West Brom in the fifth round this weekend
The Spaniard was dismissed after chopping down Sadio Mane in the second half, but substitute stopper Jussi Jaaskelainen saw out the Hammers’ clean sheet.
|VIEW FROM ST MARY'S
|By Dan Brett
It was a match which promised plenty of attacking threat as both team sheets were revealed; both sides employing three strikers as they looked for three points.
However, it was Southampton who had the better chances of the evening and Ronald Koeman and his side will be kicking themselves for only earning a point.
In truth, the Saints looked the better all-round side throughout the night but they lacked the clinical finishing to grab the win.
West Ham goalkeeper Adrian will be left red-faced after his mad red card saw Allardyce's men down to ten with 30 minutes to go, but the visitors held on for a valuable draw
Allardyce was given cause for concern, though, as Andy Carroll spent the final few minutes limping around the pitch after picking up a knock.
Southampton started brightly and James Tomkins, who signed a new long-term deal on Tuesday, underlined his value to the side with a well-timed intervention to deny Mane as the forward looked to latch on to Graziano Pelle's flick following some impressive build-up play.
Mane's direct running caused problems again in the 13th minute when he raced through on goal and looked to find the net from a narrow angle, only for Carl Jenkinson to clear after Adrian had been taken out of the equation.
It was not all one-way traffic, though, and West Ham sounded a warning shot at the other end when Morgan Amalfitano's goal-bound effort was hacked away by Steven Davis.
But it was Southampton who looked the most likely and Mane dragged a shot wide from the edge of the box eight minutes before the break to highlight the Saints' attacking prowess.
Carlton Cole, making his first start since November, was perhaps fortunate to escape a red card when he caught Maya Yoshida in the face with a high boot.
The defender received a nasty cut just below his eye, but continued after treatment, while Cole's evening was ended not long after in shambolic circumstances.
Adrian attempted to evade the onrushing Mane when a simple clearance would have averted the danger and, with the Senegal international having got a touch, the goalkeeper sought to retrieve the situation by diving on the ball outside the area, earning him a red card.
Cole made way as Jaaskelainen came on, but the Finn was surprisingly kept quiet initially, watching on as Pelle fired well over the crossbar when well placed.
Southampton continued to force the issue, though, and substitute Dusan Tadic looked to have an opportunity to shoot when he collected James Ward-Prowse's deep cross, but the Serbian dallied and the chance escaped him.
Filip Djuricic, a loan signing from Benfica, was brought on for his Southampton debut for the final 10 minutes, though his first 30 seconds on the field were spent watching a pitch invader, who was eventually escorted away by stewards.
Tadic showed good feet in the area late on, but could not get a shot away and Jose Fonte finally forced a good save from Jaaskelainen in the first of five minutes of time added on, but there was no way through for Southampton, who subsequently slipped to fourth.