The Bayern Munich central midfielder scored twice against Ireland on Friday and has won a starting spot for his country as Philipp Lahm replaces Marcel Schmelzer in defence
The Real Madrid midfielder was withdrawn at half-time during Friday's 6-1 win over the Republic of Ireland and was replaced by his Bayern Munich counterpart, who went on to score twice.
The former Leverkusen man has spoken of his desire to get more minutes for his country, and has got his wish in Berlin.
Elsewhere, Per Mertesacker retains his place alongside Holger Badstuber in the heart of defence as captain Philipp Lahm replaces Marcel Schmelzer at left-back.
Sweden have reinstalled Johan Elmander at the head of their attack, replacing Mathias Ranegie, who started the recent win over the Faroe Islands.
Alexander Kacaniklic scored the equaliser against the Nordic minnows, but will have to make do with a place on the bench, with Samuel Holmen preferred on the left wing.
Behrang Safari has taken the left-back spot from Martin Olsson, and Rasmus Elm has seen off the challenge of Christian Wilhelmsson to start alongside Pontus Wernbloom in midfield.
GERMANY (4-2-3-1): Neuer; Boateng, Mertesacker, Badstuber, Lahm; Kroos, Schweinsteiger; Muller, Ozil, Reus; Klose
SWEDEN (4-2-3-1): Isaksson; Lustig, Granqvist, J Olsson, Safari; Wernbloom, Elm; Larsson, Ibrahimovic, Holmen; Elmander