The former Amsterdam star is looking forward to Sunday's encounter, and is hopeful that the reigning champions will record a big win against their league rivals
The Uruguay international left Ajax for Liverpool in January 2011, but still has warm feelings for his former club, and Suarez is hopeful that they will make amends for the 6-2 loss in Eindhoven from April 2009.
"We once lost a game against PSV 6-2. That's why I'm hoping for a four or 5-0 win for Ajax this time around. I would really love that," Suarez told Ajax TV.
"The games against Feyenoord and PSV are always extra important. You always want to win against them. Those matches are the most important games of the year."
Sunday's Eredivisie clash at the Amsterdam ArenA kicks off at 16.30CET.
Ajax currently sit second in the Eredivisie table with 52 points from 26 games, trailing leaders AZ by one point. PSV are fourth with 51 points from 26 matches.