The duo, who missed the World Cup through injury, have been recalled by new coach Guus Hiddink for the upcoming matches against Italy and Czech Republic
The return of Rafael van der Vaart and Gregory van der Wiel headlined Guus Hiddink's first squad back as Netherlands coach.
Hiddink – who has replaced new Manchester United manager Louis van Gaal – named a 25-man squad on Wednesday in preparation for two fixtures next month, beginning with a friendly against Italy on September 5.
The nation's first Euro 2016 qualifier follows four days later against the Czech Republic in Prague.
Van der Vaart has not featured for the Netherlands since November 2013, a goalless friendly draw against Colombia.
The 31-year-old, who battled hamstring and calf problems last term, has scored seven goals in his last 12 national team appearances and, like Van der Wiel, was set to travel to Brazil for the World Cup but an injury kept him out of the tournament.
Hiddink has included two more players who did not feature at the World Cup in his squad, with Erik Pieters, and Jeroen Zoet winning call-ups too.
Of the 23-man World Cup squad, Jonathan de Guzman and Terence Kongolo have been dropped. Netherlands finished third in this year's showpiece in Brazil.
Goalkeepers: Jasper Cillessen (Ajax), Tim Krul (Newcastle United), Michel Vorm (Tottenham), Jeroen Zoet (PSV)
Defenders: Daley Blind (Ajax), Stefan de Vrij (Lazio), Daryl Janmaat (Newcastle United), Bruno Martins Indi (Porto), Erik Pieters (Stoke City), Gregory van der Wiel (Paris St Germain), Paul Verhaegh (Augsburg), Ron Vlaar (Aston Villa), Joel Veltman (Ajax)
Midfielders: Jordy Clasie (Feyenoord), Nigel de Jong (Milan), Leroy Fer (QPR), Arjen Robben (Bayern Munich), Wesley Sneijder (Galatasaray), Rafael van der Vaart (Hamburg), Georginio Wijnaldum (PSV)
Forwards: Memphis Depay (PSV), Klaas-Jan Huntelaar (Schalke), Dirk Kuyt (Fenerbahce), Jeremain Lens (Dynamo Kiev), Robin van Persie (Manchester United)