The USA coach feels that Joachim Low's side have the necessary quality and unity to beat any rival, and says that he maintains a good relationship with the current trainer
The Germans were knocked out at the semi-finals in both the 2006 and 2010 World Cups and were beaten finalists in Euro 2008.
However, the USA coach feels that Germany now boast a squad with many talents at their disposal, and can come away as victors in Poland-Ukraine.
"I hope that Germany can prevail this time. I believe that we now have a team with many different strengths, a team that can leave their mark on the Euros and win the title in the end," he told Frankfurter Rundschau.
"I think that we have the conviction, the inner-strength to say, 'No matter what comes next we can overcome it, whether's it's Spain or anyone else.'"
Klinsmann was at the helm for Germany's unsuccessful 2006 campaign, before handing the reins to current coach Low, who acted as his assistant when he was in charge.
The 47-year-old went on to say that the two had a fantastic relationship when they worked together, and that he saw Low as more than just an employee.
"Jogi Low was a true friend and not just an assistant coach. We could sit together and talk for hours."
Germany kick off their Euro 2012 campaign against Portugal on June 9.