Tottenham manager Andre Villas-Boas has made three changes to the side that beat Swansea City 2-1 for the Europa League quarter-final clash against Basel.
William Gallas, Benoit Assou-Ekotto and Lewis Holtby are all introduced for Spurs, with Michael Dawson and Gylfi Sigurdsson dropping to the bench while Kyle Walker is suspended.
It means that the hosts field their strongest attack possible as Gareth Bale and Aaron Lennon flank Emmanuel Adebayor after Jermain Defoe suffered a groin injury.
The visitors, meanwhile, include the likes of Valentin Stocker and Marco Streller in their attack but there is only a place on the bench for veteran striker Alexander Frei.
Tottenham starting XI: Friedel, Gallas, Naughton, Vertonghen, Assou-Ekotto, Parker, Dembele, Holtby, Lennon, Bale, Adebayor
Subs: Lloris, Caulker, Dawson, Huddlestone, Livermore, Sigurdsson, Dempsey
Basel starting XI: Sommer, Steinhofer, Schar, Dragovic, Voser, Elneny, Cabral, Serey Die, Salah, Stocker, Streller
Subs: Vailati, Ajeti, David Degen, Alexander Frei, Cabral, Sauro, Zoua