The two teams look set to attack as they name strong line-ups for the all-Spanish showpiece in Bucharest on Wednesday night
Luis Perea, who had been struggling with a thigh problem and will leave Atletico at the end of the current campaign, has been cut from the final squad by Simeone, but Antonio Lopez, also set to depart this summer, makes the bench for Atletico.
The 2010 winners have included Diego, Arda Turan and Adrian in an attacking trio behind Falcao, while Athletic start with Spain midfielder Javi Martinez in defence once more.
Atletico will be the 'home' side for this clash, meaning the Basques will wear their changed strip in Bucharest.
Atletico Madrid (4-2-3-1): Courtois; Juanfran, Miranda, Godin, Filipe; Mario, Gabi; Arda Turan, Diego, Adrian; Falcao
Subs: Asenjo, Antonio Lopez, Koke, Martin, Dominguez, Salvio, Assuncao
Athletic Bilbao (4-3-3): Iraizoz; Iraola, Javi Martinez, Amorebieta, Aurtenetxe; Iturraspe, Herrera, De Marcos; Susaeta, Llorente, Muniain
Subs: Fernandez, Ibai Gomez, Ekiza, Perez, Gabilondo, San Jose, Toquero