Nice's Champions League hopes were ended with a 1-1 draw at home to Lyon in the last game at Stade du Ray, while Lille drew with Montpellier as Evian and Reims secured safety
Nancy ended an eight-year stay in the top-flight after defeat to Bastia saw them consigned to Ligue 2 football next season.
After a mesmerising run of form under Patrick Gabriel to get them out of the drop zone and up to 17th place, three consecutive defeats in the last three games, coupled with Evian's late blossoming run, has seen the hosts go down.
Ilan fired the Corsicans in front soon after the break, diverting in from Anthony Modeste's pass, before Sebastien Puygrenier equalised.
With Evian leading against Valenciennes, the hosts pushed to grab the goal that would see them fight another day, but Modeste's fine finish after Claudio Beauvue's neat cut-back signalled the end of Nancy's Ligue 1 adventure.
SAINT-ETIENNE 2-0 OLYMPIQUE DE MARSEILLE
Saint-Etienne's hopes of Champions League football was boosted with a 2-0 win over Olympique de Marseille, who had nothing to play for after securing second place last week.
With the title lost to PSG, and their season objectives met, if not exceeded, it was clear to see that the visitors played with a sense of accomplishment, as the hosts dominated the early proceedings.
Loic Perrin put them ahead midway through the first half, rising highest from a corner, before former Marseille striker Brandao got one over his former employers with a well-taken second just before half-time, connecting well with Faouzi Ghoulam's cross.
Christophe Galtier's side remain in fourth place, but with Europa League football already secured following their Coupe de la Ligue triumph, they will now focus on catching rivals Lyon in third.
TROYES 1-0 BORDEAUX
A third victory on the trot saw Troyes rise above relegated Nancy and remain in contention for survival after a narrow 1-0 victory over ten-man Bordeaux.
Having lost to les Girondins in Tuesday's Coupe de France semi-final, the Champagne side were hoping to secure the three points which could see them closer to safety, having spent the entire season in the drop zone.
And Frederic Hantz's men didn't disappoint, as they controlled Bordeaux for large periods of the game, with the visitors appearing distinctly narrow and lethargic.
The game's winning goal was scored by Fabien Camus on 56 minutes, whose fine effort beat Cedric Carrasso, before Bordeaux saw Julien Faubert sent off nine minutes later. Cheick Diabate's header hit the woodwork late on, as Troyes held on to fight another day.
EVIAN 2-0 VALENCIENNES
Evian secured Ligue 1 survival with a comfortable 2-0 win over a disappointing Valenciennes' side at Parc des Sports in Annecy.
Saber Khlifa, scorer of last week's outrageous 60-metre goal against Nice, found the net once, in albeit less impressive circumstances, firing in from Fabrice Ehret's pass inside two minutes.
The roles changed ten minutes later as Khlifa reciprocated the favour, teeing up Ehret to make it 2-0 on 12 minutes.
Valenciennes were marshalled well throughout, though Nicolas Penneteau thwarted a third, being forced into a smart stop from a powerful effort from Daniel Wass. Nevertheless, Evian can look forward to a third Ligue 1 campaign next year.
SOCHAUX 1-2 TOULOUSE
Sochaux's defeat to Toulouse means that they remain precariously above the drop zone after a narrow 1-2 loss against Alain Casanova's men in Montbeliard.
The visitors started positively, despite playing for nothing more than pride, and they raced into an early lead. Adil Hermach's effort could only be parried by Simon Pouplin, as Issiaga Sylla rebounded to pick up his first senior goal.
It was 2-0 to the visitors soon after, as Adrien Rabiot picked a superb pass out to Jean-Daniel Akpa-Akpro, who fired past Pouplin to double his side's advantage.
Giovanni Sio pulled one back for the hosts, powerfully placing the ball past Ali Ahamada, but even with Etienne Capoue's red card later in the game, the hosts will be looking nervously over their shoulders with Troyes still able to catch them on the final day next weekend.
MONTPELLIER 0-0 LILLE
Lille's Champions League hopes took a further blow on Saturday night as they were held to a 0-0 draw by mid-table Montpellier at Stade de la Mosson.
In what was Rene Girard's final home game as MHSC coach, a year to the day after he won the Ligue 1 title, Montpellier's disappointing campaign will now see them finish outside the European places, though Lille are in danger of following them too after a lethargic display.
With nothing to separate the two sides, it was a game of few clear-cut chances, with Dimtri Payet and Co. unable to unlock a solid Herault defence.
Lille sit on 61 points, behind Saint-Etienne, Lyon and Nice in the race for Champions League qualification, which will head into the final day.
STADE RENNAIS 1-1 AJACCIO
Ajaccio failed to mathematically secure Ligue 1 survival as they were held to a 1-1 draw against Stade Rennais at Stade de la Route de Lorient.
Frederic Antoinetti presided over his final home game as Rennes boss following a five-year spell, but it was the visitors who threatened to spoil the occasion, as they took the lead inside five minutes thanks to Fousseini Diawara, who turned Benjamin Andre's shot past Benoit Costil.
The hosts rallied, and equalised in stoppage time of the first half as Steven Moreira's cross was met emphatically by Mevlut Erding.
Neither side could find a second, with Ajaccio now hovering above the drop zone on 40 points, but a Troyes win and a seven-goal swing in goal difference could see them go down next week.
STADE DE REIMS 1-0 FC LORIENT
Stade de Reims secured Ligue 1 survival with a narrow 1-0 win over Lorient, as they moved up to 14th place on 42 points.
The winner came from the penalty spot, after Diego Rigonato - who later was stretchered off - dribbled his way into the box before Lamine Gassama's foul ensured the referee pointed to the spot. Up stepped Gregorz Krychowiak to fire his fourth Ligue 1 goal of the season.
The Poland international, who has also scored the winner against Lyon and PSG this season, was instrumental throughout the game, as Lorient looked disappointing up front without top scorer Jeremie Aliadiere.
NICE 1-1 OLYMPIQUE LYONNAIS
The game, originally scheduled for Saturday evening along with the other nine fixtures, was postponed until Sunday afternoon due to inclement weather in the Cote d'Azur region.
But Nice's spirits weren't to be dampened in the last-ever game at the historic Stade du Ray, with the south coast side moving into the Allianz Riviera next year.
After a first-half of attacking intensity coupled with poor finishing, it was the hosts who took the lead in controversial circumstances, with Dario Cvitanich scoring from the penalty spot despite minimal contact made by Bakary Kone.
Bafetimbi Gomis wasted a great chance, but Lyon's hopes seemed to fade once captain Maxime Gonalons was sent off - but a minute later, their luck would change. Clement Grenier fired an exquisite Juninho-esque free-kick from 30 metres past David Ospina, and salvaged a point for the visitors.
Whilst a win would have confirmed Champions League qualification, Lyon now sit on 64 points, two ahead of Saint-Etienne and three clear of Lille. Nice can secure Europa League football next weekend.