Reports in the Swiss media claim the London club have made an approach for Yakin, who was also quoted as saying he had been in contact with the Premier League outfit.
|14/1||Murat Yakin is 14/1 with Coral to be the next Tottenham manager|
He told Swiss newspaper Blick: "There has been no contact between the clubs."
Despite Yakin being quoted on Tuesday as saying he had been approached by Tottenham, the former Switzerland defender has now denied making such a claim.
He said: "I am enjoying my holidays. I have had no contact with Lazio or Tottenham."
Tim Sherwood will take charge of Tottenham's Capital One Cup quarter-final against West Ham, with the club prepared to make their former midfielder the next permanent manager if he impresses during the interim.