The Paris Saint-Germain defender is the notable absentee from Louis van Gaal's provisional group, with Augsburg's Paul Verhaegh instead handed a placeGregory van der Wiel is the most notable absentee from Netherlands' 30-man provisional World Cup squad.
The Paris Saint-Germain defender, capped 37 times by the senior Oranje side, has been overlooked in favour of Augsburg's Paul Verhaegh.
Robin van Persie, Arjen Robben, Wesley Sneijder and Rafael van der Vaart are all included in the initial squad, as have Nigel de Jong and Dirk Kuyt.
Young Feyenoord defender Terence Kongolo is handed a place as Louis van Gaal looks to experiment with a 5-3-2 system to compensate for the injured Kevin Strootman. Celtic centre-back Virgil van Dijk, however, is not included.
Squad in full:
Goalkeepers: Jasper Cillessen (Ajax), Michel Vorm (Swansea City), Tim Krul (Newcastle United), Jeroen Zoet (PSV)
Defenders: Paul Verhaegh (Augsburg), Patrick van Aanholt (Vitesse), Daryl Janmaat (Feyenoord), Joel Veltman (Ajax), Stefan de Vrij (Feyenoord), Ron Vlaar (Aston Villa), Bruno Martins Indi (Feyenoord), Karim Rekik (PSV), Terence Kongolo (Feyenoord), Daley Blind (Ajax)
Midfielders: Leroy Fer (Norwich City), Nigel de Jong (AC Milan), Jordy Clasie (Feyenoord), Jonathan de Guzman (Swansea City), Georginio Wijnaldum (PSV), Wesley Sneijder (Galatasaray), Rafael van der Vaart (Hamburg), Tonny Vilhena (Feyenoord)
Forwards: Quincy Promes (Twente), Arjen Robben (Bayern Munich), Jean-Paul Boetius (Feyenoord), Robin van Persie (Manchester United), Klaas-Jan Huntelaar (Schalke), Dirk Kuyt (Fenerbahce), Jeremain Lens (Dynamo Kiev), Memphis Depay (PSV)