The 25-year-old may find first-team football hard to come by at the Philips Stadion and could now be set to link up with former coach John van den Brom in Brussels
The centre-back joined the Eindhoven club from ADO Den Haag, and could soon be reunited with his former coach from the Kyocera Stadion, John van den Brom, in Brussels.
The two enjoyed a successful season together in 2010-11 when the club from The Hague achieved Europa League qualification, only to be knocked out in the preliminary stages of the competition in the following campaign.
Reports suggests that PSV and Anderlecht have already discussed the 25-year-old's return to his native country.
The Belgian is unlikely to get regular action at the Philips Stadion following the arrival of Mathias Jorgensen, who is expected to form a defensive partnership with Marcelo.