He joins summer signings Sebastian Coates and Craig Bellamy among the replacements, as Liverpool pick a strong 4-4-2 formation with Carroll joining Luis Suarez up front.
Meanwhile, Tottenham keep the same side that defeated Wolves 2-0 in their last Premier League game, with Ledley King earning a place in the starting XI again.
Dutch midfielder Rafael Van der Vaart has recovered from a hamstring problem, but can only make the bench.
Tottenham (4-4-2): Freidel; Assou-Ekotto, King, Kaboul, Walker; Bale, Parker, Modric, Kranjcar; Defoe, Adebayor.
Subs: Cudicini, Bassong, Corluka, Van der Vaart, Livermore, Pavyluchenko, Giovani
Liverpool (4-4-2): Reina, Agger, Skrtel, Carragher, Enrique; Downing, Lucas, Adam, Henderson; Carroll, Suarez.
Subs: Doni, Coates, Robinson, Maxi, Spearing, Kuyt, Bellamy
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