subs: Amos; Gill, Anderson, Nani; Owen, Berbatov, Hernandez
West Ham: Green; Jacobsen, Bridge, Da Costa, Upson; Parker, Hitzlsperger, Noble, O'Neil; Ba, Cole.
Subs: Boffin; Reid, Tomkins, Spector; Piquionne, Obinna, Keane
Thomas Kuszcak coming in to replace Edwin Van Der Sar in goal for Manchester United is the big shock in the teams coming from Upton Park.
Manchester United have gone with Rooney up-front on his own with Berbatov and Hernandez having to be content with a place on the bench.
West Ham are unchanged from the draw with Tottenham before the international break with Scott Parker being passed fit to start after he was a doubt with shoulder and calf injuries.
Manchester United will be aiming to avoid a re-occurrence of their last visit to Upton Park when they were comprehensively beaten 4-0 in the quarter final of the FA Cup.