Fabregas maintains that Wenger is loyal to the club and has something to prove in the Premier League, and wants to succeed with a youthful squad.
Questioned about whether the Frenchman was up to the job, Fabregas focused on Wenger’s commitment.
"Yes, yes, of this I'm sure," the 23-year-old told The Sun.
"I can guarantee you that, 100 per cent. I have been here for seven years, I'm now in my eighth year so I know him very well and I can tell you he is more focused than ever. He wants to win and he wants to prove that this young team can be winners, can be successful. That's his dream and he's working very hard for it."
Arsenal were booed off after their 1-0 defeat by Newcastle at the Emirates last weekend, following another goalkeeping error from Lucasz Fabianski.
Fabgregas was the subject of intense speculation in the summer following a successful World Cup in South Africa, with a move away from the Emirates to Barcelona widely expected, only for the Gunners to reject a £35m bid for the Spanish star.
Asked if it has been a problem refocusing after winning the World Cup, and if resuming Premier League football felt like an anti-climax, Fabregas was adamant.
"No, not at all," he said. "I was honest about it all at the time and I think they understood the situation perfectly, 100%.
"There has not been one single person either at the stadium or in the street who has said anything bad to me about it - no, no. Nothing, nothing at all and that's been very welcome and appreciated.
"I am just focused on having a great season at Arsenal and winning something."
Fabregas reaffirmed his commitment to Arsenal for the season and vowed to concentrate on winning a trophy once again, yet struggled to decide if he'd prefer to win the Premier League or the Champions League.
"That's a difficult one.
"I must say I would be very proud to win the Premier League but - and maybe a lot of the fans are against me in this - winning the Champions League is the one thing I would like to win the most. After winning the European Championships, then the World Cup, the Champions League is the next big one for me."
Arsenal face Everton at Goodison Park on Sunday.