Isaac Vorsah also fit to start
The 25-year old had feuded with the Serb after being left on the substitute's bench for the Black Stars earlier matches at the tournament. With Andre Ayew suspended, Muntari has been brought back in to strengthen the midfield.
At the back, Isaac Vorsah has shaken off injury to partner skipper John Mensah. This move sees the inexperienced Jonathan Mensah - who had been struggling with a knock - return to the sidelines.
Uruguay head coach Oscar Tabarez announced his selection on Wednesday, with two changes made to the team that beat Mexico. In midfield, Alvaro Fernandez has replaced Alvaro Pereira, while at the back Mauricio Victorino will stand in for the injured Diego Godin.
Uruguay: Muslera; Maxi Pereira, Lugano, Victorino, Fucile; Fernández, Pérez, Ríos; Forlán; Cavani and Suárez
Ghana: Kingson; Pantsil, Mensah, Vorsah, Sarpei; Annan, Prince Boateng, Inkoom, Muntari; Kwadwo Asamoah, Asamoah Gyan