Real Madrid and Barcelona will meet for the first time this season on Saturday, October 26 at 18:00 CET at Camp Nou, the LFP announced.
The time was made official on Monday afternoon, and it will serve as the 10th league match of the season for each team.
It is the first Clasico for both coaches - Madrid's Carlo Ancelotti and Barcelona's Gerardo Martino - while it is also a first taste for Barca's Neymar and los Blancos' Gareth Bale, Isco, Asier Illarramendi and Daniel Carvajal.
Real Madrid have not lost a league match to Barcelona since December 2011, winning 2-1 at the Bernabeu last season, while earning a 2-2 draw and a 2-1 victory in their previous two league trips to Camp Nou.
Lionel Messi needs one goal to pass Real Madrid legend Alfredo Di Stefano to become the Clasico’s all-time leading scorer.
Both teams have Champions League games scheduled in the week leading up to the match, as Barcelona travel to play Milan at San Siro on Tuesday evening, while Real Madrid will host Juventus on Wednesday.