The former Valencia wing-back could face a spell on the sidelines after he picked up a thigh injury while away on international duty
The left-back picked up a thigh problem in the closing stages of Spain's 1-1 World Cup qualification draw against Finland on Friday evening, and could be out of action for a number of weeks as a result.
Alba left Spain's training camp on Saturday, and is now certain to miss Tuesday's clash with France and is a major doubt ahead of the Champions League quarter-final with Paris Saint-Germain.
"The obligatory medical tests on Jordi Alba in the morning have found a grade one muscle injury in the femoral biceps of his right thigh. He has left the camp," a team statement read.
Alba's injury comes only a week after fellow full-back Adriano was ruled out for up to six weeks with a hamstring problem.