The Gunners have endured tough trips to the Britannia Stadium in recent years, but the Czech Republic international believes they can deal with Mark Hughes' side's tough approach
The Gunners have only returned with all three points once in their last five Premier League visits to the Britannia Stadium, failing to win their past three encounters in Staffordshire.
Arsene Wenger's men sit just one point behind leaders Chelsea heading into Saturday's game and midfielder Rosicky wants Arsenal to be ready for Stoke's "aggressiveness" in order to keep their Premier League title bid on track.
"[I'm expecting] a typical game when you go to Stoke," he told the club's official website. "It's always very similar - they are a very physical side, very aggressive and it's a very tough place to go.
"All the away games are pretty similar so we need to be really well-prepared [for a] physical and aggressive style of play. We need to match them in those attributes and, if we do that, we can be successful.
"For me, (the crowd at the Britannia) doesn't matter at all. The atmosphere in the stadiums here in England is great anywhere you go, so that side doesn't bother me at all.
"What I'm thinking about is (what performance) we will produce on the pitch and if we will be as aggressive and strong as Stoke. If we do that, we can beat them."
The visit to Stoke is the Gunners' last Premier League game for over a fortnight as they face Everton in the last eight of the FA Cup and take on Bayern Munich in the second leg of their Champions League clash before resuming domestic duty with the north London derby against Tottenham on 16 March.