The Red Devils are on course to lift their 20th top-flight title having opened up a 15-point gap to second-placed reigning champions Manchester City.
But, whilst the Dane admits his side are in a "comfortable position", he insists the likes of Ryan Giggs, Paul Scholes and captain Nemanja Vidic are ensuring complacency does not creep in.
"We are at a crucial stage of the season and have to stay sharp," he told MUTV.
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"I think it's very important for us not to look at the table right now. People from outside will say we've put ourselves in a comfortable situation but it's very important for us to take it game by game so we don't get to relax.
"Of course, it's a good position to be in but it's something we cannot think about. I think you can feel it in the team now, especially with the more experienced players, that we're entering the late stage of the season when all the medals are going to be given out.
"From Rio [Ferdinand], Giggsy, Scholes and Vida, you can really feel it with the players who have done it before and see how determined they are and how important it is to them.
"The younger and less experienced players try to look to them leading us in the right direction, reminding us every day to stay sharp, not to relax and to keep going."