The 39-year-old midfielder will have to wait at least one more game for the landmark occasion as Sir Alex Ferguson names a strong starting XI against Chris Hughton's sideRyan Giggs will have to wait for his 1000th appearance for Manchester United after being left out of the squad to face Norwich City.
Sir Alex Ferguson has named a strong line-up despite facing a crucial Champions League clash with Real Madrid on Tuesday evening, with Wayne Rooney and Robin van Persie starting up front.
There's no space in the squad for Rio Ferdinand as Chris Smalling, Nemanja Vidic and Jonny Evans play in defence with Patrice Evra, whilst Anderson and Shinji Kagawa have also been handed starting roles.
Grant Holt is selected up front for Chris Hughton's side as they look to build on their fine late win over Everton, with other forwards Luciano Becchio and Kei Kamara forced to settle for places on the bench.
The Canaries could prove tough opponents having conceded just two goals in their last four Premier League games, although the home fans will expect Mark Bunn to be busier than David de Gea at Old Trafford.
Manchester United starting XI: De Gea; Smalling, Vidic, Evans, Evra; Valencia, Carrick, Anderson, Kagawa; Rooney, Van Persie.
Subs: Lindegaard, Rafael, Chicharito, Nani, Young, Welbeck, Cleverley.
Norwich starting XI: Bunn; R Martin, Bassong, Turner, Garrido; Johnson, Snodgrass, Howson, Pilkington, Hoolahan; Holt.
Subs: Camp, Whittaker, R Bennett, Fox, E Bennett, Kamara, Becchio.