The Red Devils can close the gap between themselves and Roberto Di Matteo’s side in the Premier League table to just point with a victory at Stamford Bridge on Sunday, before returning on Wednesday for their League Cup fourth-round tie.
Scholes has recognised United’s below-par record against Chelsea in recent years, and complimented the team’s change in direction through the use of "smaller, better footballers", but remains hopeful of victory.
"We've got three massive games really in a week," Scholes told MUTV.
|Chelsea v Man Utd preview
"Obviously Chelsea twice and then Arsenal at home. Sunday is a big one. We've not got a brilliant record at Chelsea over the last few years and it's something we hope we can change.
"We watched them against Tottenham last week. They've signed a different type of player to a couple of years back when you were looking at a big, powerful team.
"Now they've signed smaller, better footballers who are difficult to play against. We know each of them is capable of creating chances and scoring goals themselves.
"They're a good team to play against because they like to play football and you always get a fair share of the ball there and a fair share of the chances. There's always a good atmosphere and we want to change the results we've had over the years there."