The goalkeeper was rarely tested en route to achieving his second clean sheet of the group stages although he did look vulnerable dealing with high balls into the box.
The experienced 37-year-old captain led the defensive line brilliantly and was dominant in the air.
His pace ensured that he was rarely beaten by McManaman and his ability to surge from box-to-box meant that he was a key member for both the defence and the attack. He picked up an injury and was replaced at half time.
The right-back was always willing to get forward to aid the attack and he got in behind McClean to score the opening goal, thumping a shot past Nicholls.
The rugged Spanish defender dealt well with the physical presence of Holt despite picking up a yellow card.
He provided an excellent shield to the back four and hardly put a foot wrong, dominating in the midfield.
The Finland international proved an excellent creative outlet for Rubin with his ability to pick out a teammate in space.
He showed some neat touches in the hole behind Mukhametshin but did not test Nicholls as much as he would perhaps have liked.
Despite spurning a good early chance, he was a constant threat down the right and combined well with Kuzmin.
The Israel midfielder created a number of good chances with his excellent vision and his precise through ball set up Kuzmin's opener.
The striker was well marshalled by Rogne throughout the match and consequently found it very difficult to get his shots away.
The young goalkeeper stepped up to the occasion and while he could do little to prevent the opening goal, he showed good reflexes and command of his area to keep the scoreline down.
He won the majority of his aerial duels and was rarely exposed down his wing. However, the deliveries of his long throws were often poor and easily defended by Rubin.
The Norwegian defender was impressive at the back for Wigan, making several brilliant interceptions. Came desperately close to scoring when he powered against the crossbar late on.
He helped to break up play effectively but found himself often outclassed by the Rubin midfield trio.
The centre-back was caught out of position on a few occasions but proved commanding from set pieces at both ends of the pitch.
The left-back found it difficult to cope with the intelligence of Ryazantsev though he did produce a crucial interception late on to deny Wigan going further behind.
The Honduran battled tirelessly in the midfield and his accurate passing was at the heart of most Wigan attacks. Provided a brilliant cross for Rogne's header which hit the bar.
The Wigan captain produced a strong tackling performance in the midfield and offered protection to the defence.
The Ireland winger was always willing to take his man on and get crosses into the box. However, his lack of concentration and failure to track Kuzmin led to Rubin's opener.
The striker's search for a first European goal continues as he was well contained by the Rubin centre-backs. He made some impact in the air but offered little with the ball at his feet.
Rubin clearly identified him as the dangerman and every time he got the ball he was surrounded by burgundy shirts. The tactic worked as McManaman was hauled off, a frustrated figure, late on.