The Uruguayan is unlikely to start as he will only return from international duty on Friday morning, with les Parisiens looking to maintain their lead at the top of Ligue 1Zlatan Ibrahimovic will get the opportunity to take his frustration out on Reims when Paris Saint-Germain travel to Stade Auguste Delaune but fellow forward Edinson Cavani is unlikely to start.
The prolific striker scored twice in Sweden's World Cup play-off second-leg defeat to Portugal at the Friends Arena in Solna, with Cristiano Ronaldo's hat-trick sealing a 4-2 aggregate win for the visitors as well as their passage to Brazil.
Ibrahimovic has scored 16 goals in his last 10 games in all competitions and coach Laurent Blanc is convinced that the former Barcelona man is ready to turn his attention back to helping PSG challenge for honours.
Cavani, meanwhile, will feature in the World Cup after Uruguay drew 0-0 with Jordan in the second leg of their play-off on Wednesday to seal a 5-0 overall success, but he may be rested this weekend.
Blanc revealed that the former Napoli man is due back from international duty on Friday morning and hinted that he is unlikely to be thrust straight back into Ligue 1 action.
The former France coach also revealed that Marco Verratti could be back in contention after recovering from a knee injury.
PSG remain unbeaten in the French top flight and have a four-point lead over Lille ahead of their clash with sixth-placed Reims on Saturday.
The hosts had won three consecutive Ligue 1 games before they were held to a goalless draw at struggling Lorient prior to the international break.
Hubert Fournier's side have been beaten only twice in the league and they would be in an even more lofty position had they been able to convert some of their seven draws into victories.