The Spaniard proved a solid pair of hands when dealing with crosses into the area, although he was barely tested by the visitors.
The Spaniard had a solid game in the heart of the defence alongside Manolas and proved himself to be very astute in the air.
Showed plenty of confidence as he regularly pushed on and got into some dangerous areas but left space in behind him a few too many times.
Put in an industrious performance in the deep-lying midfield role, and his mishit shot ended up earning him an assist for Dominguez's goal.
Showed great determination to close the opposition when not in possession, but he lacked conviction when attacking the opposition.
Played as the lone striker in place of the injured Saviola and displayed good movement and a sound ability to hold up the play, earning an assist for the second goal.
Consistently got up to support the forwards and was composed in possession. He did not allow the pace of Young to better him.
Saw plenty of the ball in midfield and distributed it well, directing his team into dangerous areas and always making himself available.
The Arsenal loanee played from the right and linked well with his team-mates before capping his appearance with a brilliant left-footed goal.
An impressive performance from the Argentine as he scored a clever goal to give his side the lead and floated about to prove a real danger to the visitors.
The keeper could do little to keep either of the goals out but his kicking was not up to standard as he put his team-mates under some unnecessary pressure at times.
Picked up an early booking for handball but used his experience to keep a cool head and not allow much past him for the remainder.
Looked rusty as he sent a number of long passes far from their intended targets and needlessly conceded possession due to a sloppy touch.
Made hasty decisions when put under pressure which caused a number of misplaced passes. He allowed Perez to cut inside of him too many times.
The Serbian was a rare shining light for United as he read the play exceptionally well to make a number of crucial interceptions and blocks.
Lacked urgency and was not strong enough to break apart the play when Olympiakos came forward. He was poor in possession before being withdrawn.
Always looked to pick up the ball from the defence and find a team-mate with a forward-thinking pass, but too often he slowed the tempo down when it needed to be raised.
The winger failed to provide anything of substance throughout the game, his crossing was sporadic and poor and he did not utilise his pace.
Helped out defensively but failed to provide any sort of attacking quality from the right with an evident lack of intent and seemingly desire.
Regularly dropped deep to pick up the ball but it meant he was playing far too far away from goal and did not link with Van Persie enough.
R. van Persie
Made a couple of clever runs in the first half but was extremely quiet until blazing his side's best chance of the night over the top late on.