Untroubled for most of the match but could do nothing about Defoe's powerful strike or Chadli's guided finish.
Read the game well for the best part but was caught standing for both Spurs goals in the first half and that proved the difference.
Made a couple of telling interceptions in the box and stood firm as Spurs rarely got in behind apart from the two goals.
Launched a couple of dangerous passes over the Spurs defence and got forward well on the right but struggled when the visitors doubled up on the flank.
It was hard to tell if he was playing full-back or winger as Walker got in behind him so often and it proved costly as the Spurs defender set up the second goal. More disciplined after the break but hardly contributed.
Tried to close down the Spurs midfield but found himself swamped and too often failed to provide protection for the back four.
Very quiet in the first half but shifted wide after the break and looked a real threat, getting in behind Fryers and linking up well with Angbwa on the flank.
Largely anonymous but did help the hosts get behind Spurs in the first half and had more of an outlet for his passing when Traore came on.
Made a lively start, getting in behind the defence more than once and looking like Anzhi's best attacking option as he regularly switched flanks.
Very quiet in the opening period as most of Anzhi's attacks went through the wings and was unsurprisingly replaced by Traore at the break.
Spent most of his time on the left-hand side and found space behind Walker, but could not produce a telling final ball before coming off early in the second half.
A relatively comfortable opening for the Spurs shot-stopper as Anzhi failed to trouble him save for the odd blocked cross but he looked strong when called upon as the hosts grew in the second half.
Reasonably solid at the back - and needed to be, with Chiriches looking nervous. Caught out by a couple of high balls early on but covered Fryers well out wide before going off injured.
Often remembered more for his attacking prowess than his defensive ability and, once again, that was the case as he looked devastating going forward - but he did leave Chiriches exposed a couple of times.
A shaky performance as he struggled to deal with Anzhi's long balls and generally looked nervy but recovered well from his mistakes more than once.
Looked very comfortable in the first half but had a lot to deal with in Ahmedov and Angbwa after the break, needing help from Kaboul more than once.
Ran the show in midfield for Spurs, helping them dominate in the middle of the park as he closed the Anzhi players down while showing some superb close control on the ball.
A real powerhouse in the Spurs midfield, the Brazilian was very often the passer before Holtby's killer ball and was always tracking back.
Lovely ball for Defoe for the opener before sliding another through for Walker in the build-up to the second. Constantly found gaps and saw dangerous passes but drifted out of the game slightly in the second half and came off with just over 10 minutes left.
Reasonably quiet in the opening period but still saw plenty of the ball as Spurs dominated. Took his goal well with a cool finish but left Fryers isolated on a few occasions.
Played a very quiet role as Spurs struggled to get in behind too often but took his goal as emphatically as you would expect.
A hit-and-miss performance from the stylish midfielder. Popped up in all areas of the pitch, showing good touches, but his passing was often loose.
Replaced Serderov early in the second half and was involved straight away, getting well forward on the left-hand side and firing in some dangerous balls.
Replaced Abdulavov at half-time despite nursing a shoulder injury and immediately added another dimension, linking up play well and adding some power to the front line.