The controversial attacker remains upbeat about his side's chances of making it to the knockout stages of the Confederations Cup
The South Americans cannot afford to slip up in their remaining two Group B games, but the Liverpool star has stressed that they are used to playing under pressure and has little doubt they will eventually progress.
"Even before the game we knew that Spain were a better side than us. We lost against the world’s best national team, but we know that the competition’s only just starting," Suarez told Fifa.com.
"The matches we’ve got coming up are different, and we’ve got to win them to progress. I think we showed a positive attitude and I’m feeling optimistic.
"Uruguayans are used to having it tough. For that reason, we’re not really worried. You just have to look at how we went into the last World Cup and also the result we just picked up in Venezuela. We’re going to get the best out of ourselves.
"Uruguay can go toe-to-toe with anybody, we’re fully aware of that. We might have had a setback against Spain, but there’s still a long way to go and we’re going to bounce back."
Uruguay take on Nigeria on matchday 2 on June 20.