The Leesiders host Douglas Hall in the Munster Senior Cup on Sunday but Caulfied stressed that the league is the priority
Following the 3-0 victory away at Athlone Town on Friday, the Leesiders are tied on 10 points with Shamrock Rovers at the summit of the league and Caulfield is keen to rotate his squad to ensure his players are fresh and injury-free for the clash against Trevor Croly's side at Turner's Cross on April 4.
"They come thick and fast," he told the club's official website. "It's hard on the guys because they've played so much.
"Obviously all the lads that are on the bench are going to get a run on Sunday and we hope they perform because we can't take a chance with the lads in the starting team, with the injury situation so early in the season.
"We'll give the lads who are on the bench a game, with some of the Under-19s on Sunday, because obviously the priority is next Friday: Rovers at home.
"We need to be up for that because Rovers are serious contenders this year. We need to be on our game to give them a game."
Cork City take on Douglas Hall in the Munster Senior Cup at Turner's Cross on Sunday March 30. Kick off 12:00 IST.