The Hull City winger will undergo surgery during the international break while Jon Walters should be fit for the international double-header
The 21-year-old, who scored the winning goal for Hull City against West Ham on Saturday, has been carrying a hernia injury and will undergo surgery to correct the problem during the international break, meaning he will miss the final two games of the campaign for Ireland.
Stoke City striker Jonathan Walters has also emerged as a doubt for the Boys in Green as he picked up a groin injury over the weekend.
The Football Association of Ireland this afternoon confirmed that Brady would miss the World Cup qualifiers, but stated that Walters remains in contention following a scan. The striker's status will be monitored by Noel King and his management team ahead of the international fixtures to ensure he is fit to play for Ireland.
The Republic of Ireland take on Germany in Cologne on October 11, with Kazakhstan visiting the Aviva Stadium four days later.