Anders Lindegaard replaces David De Gea and Ryan Giggs - the match winner in the corresponding fixture last year - replaces Scholes as United take on an unchanged Canaries XI
Sir Alex Ferguson brings in Anders Lindegaard to replace De Gea, while 38-year-old Ryan Giggs - who won this same fixture last season with a fine last gasp volley - steps in for Paul Scholes in the middle of the United midfield.
Norwich meanwhile, name an unchanged starting XI from the side that drew 0-0 away at Reading last week as Chris Hughton retains his captain Grant Holt up front in a 4-5-1 formation.
The Canaries are looking to extend an unbeaten run that has now reached five consecutive games, including the scalp of Arsenal in the league and Tottenham in the Capital One Cup.
Norwich City: Ruddy; Whittaker, Bassong, Turner, Garrido; Snodgrass, Johnson, Tettey, Pilkington; Hoolahan; Holt
Subs: Bunn, Howson, Jackson, Morison, Elliott Bennett, Tierney, Ryan Bennett.
Manchester United: Lindegaard; Rafael, Ferdinand, Smalling, Evra; Valencia, Carrick, Giggs, Young; Chicharito, Van Persie.
Subs: Johnstone, Jones, Anderson, Welbeck, Scholes, Cleverley, Fletcher.