The Switzerland coach is certain that the Bundesliga's two leading clubs will meet at Wembley in May
In the first leg of the semi-finals, the Bavarians beat Barcelona 4-0, while Die Schwarzgelben will go into their second-leg match against Real Madrid with a 4-1 advantage.
And Hitzfeld does not believe the two Spanish clubs will be able to turn around their ties at home this week.
"I still remain convinced that Dortmund will reach the final, where they will meet FC Bayern, but it won’t be easy," the 64-year-old told Bundesliga.com.
"I believe that neither Dortmund nor Bayern will lose in Spain."
Hitzfeld, who won the Champions League as a coach with both Dortmund and Bayern, was impressed by the way his former clubs defeated the two Spanish giants, and feels there may be a changing of the guard in Europe.
"If you consider that the Bundesliga leaders beat the Liga leaders 4-0, and the Bundesliga’s second-placed side that of La Liga 4-1, then the goalposts really have been moved," he added.
"There is a changing of the guard taking place, but Dortmund and Bayern need to confirm that in the second legs.
Dortmund will play their second leg against Madrid on Tuesday, while Bayern face off against Barca at Camp Nou on Wednesday.