The Paris Saint-Germain defender and AC Milan midfielder had fallen out of favour with Oranje in recent times, with Van der Wiel returning after over a year in international exile, while De Jong last featured for the national team in November 2012.
Furthermore, PSV youngster Memphis Depay could make his debut for Holland after impressing in the opening months of the 2013-14 campaign. The winger, 19, has already represented Netherlands at Under-17, U-19 and U-21 level, but has yet to make his first appearance for the senior side.
Goalkeepers Maarten Stekelenburg and Jeroen Zoet both miss out due to injury, while Paul Verhaegh, Ruben Schaken and Ricky van Wolfswinkel didn't make the cut after they were included in the provisional squad.
Netherlands have already secured top spot in their section to secure qualification for next year's tournament in Brazil.
|Michel Vorm||Swansea City|
|Tim Krul||Newcastle United|
|Ron Vlaar||Aston Villa|
|Bruno Martins Indi||Feyenoord|
|Stefan de Vrij||Feyenoord|
|Gregory van der Wiel||Paris Saint-Germain|
|Rafael van der Vaart||Hamburg|
|Nigel de Jong||AC Milan|
|Jonathan de Guzman||Swansea City|
|Robin van Persie||Manchester United|
|Arjen Robben||Bayern Munich|
|Jeremain Lens||Dynamo Kyiv|