The international midfielder believes that Sunday's fixture could give his side a huge boost in their attempt to wrest the title away from the Spanish champions
Barcelona playmaker Andres Iniesta has labelled the Clasico against Real Madrid as a great chance for his team to maintain their early lead at the top of the Primera Division.
Jose Mourinho's men have stuttered during the opening weeks of the campaign, and Iniesta is keen to heap additional misery on their title rivals by securing a valuable victory on Sunday.
"We have the opportunity to take a great advantage against a direct rival," proclaimed the 28-year-old to ESPN. "This game is a different one to all the others, one with a lot of tension.
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"The start of the season was a good one and the team are doing well, but now we have to keep getting better."
The Euro 2012 winner is in prime contention for this year's Ballon d'Or, alongside fellow Clasico protagonists Cristiano Ronaldo and Lionel Messi.