The Portuguese coach is allegedly eager to jump at the chance to take the reins of the Catalan team and told his representatives to let the Blaugrana know he is available
It is believed that Villas-Boas' entourage has contacted Barca in an unofficial manner to let the Blaugrana know about the 34-year-old's availability.
Villas-Boas took over from Chelsea last summer after guiding Porto to four titles in 2010-11, but he was sacked by the Blues following a run of three Premier League victories in 12 games.
He has been strongly linked with Inter's hot-seat, but such reports have cooled following Andrea Stramaccioni's positive start at San Siro.
The Portuguese coach has now reportedly turned his attention to the Catalan club as doubts remain about Guardiola's Blaugrana future.
The 41-year-old, whose Barca contract expires at the end of the season, stated after the club's Champions League elimination against Chelsea that he would decide his future 'in the next few days'.
It is understood, however, that if Guardiola decides against extending his stay at the club, Athletic Bilbao coach Marcelo Bielsa is red-hot favourite to be the Spaniard's successor.
Spanish sources claim that Guardiola will address the media alongside club president Sandro Rosell on Friday morning after the team's training session.