It was thought that the Argentine might be asked to play deeper to allow the Uruguayan to lead the line, but the coach is unwilling to place any restrictions upon his No.10
Speculation has been rife ahead of the 2014-15 campaign that the new Blaugrana coach will ask his No.10 to accept a more withdrawn attacking role this term - as the Argentina international did during this summer's World Cup - so as to allow summer signing Luis Suarez to play in his preferred position of centre-forward.
However, Luis Enrique has now confirmed that Barca's attack will once again be based around Messi.
"Leo has so many options that we can't close off any to him," the former Spain international told reporters on Sunday. "He will have total freedom to move in attacking situations.
"He is the best in the world, without a doubt, and we adapt to his mobility."
Luis Enrique also refused to confirm whether he intends to primarily employ the versatile Javier Mascherano as a centre-half or in front of the back four this season.
"I love him as a defender and a midfield pivot," the coach enthused. "We'll see him in both positions."
Luis Enrique added that Mascherano could feature in Monday's friendly against Mexican outfit Club Leon, but that neither Messi nor Neymar will feature.
"We're not at 100 per cent, which is no surprise at this stage," the Barca boss stated. "But the squad have trained harder than I expected.
"They have made sacrifices and I am 100 per cent optimistic. The fans will like what they see [on Monday]."