Ghana midfielder Emmanuel Agyemang-Badu will not be part of the 21-man squad released for the crucial Africa Cup of Nations qualifier against Malawi.
The Udinese midfielder suffered a knee injury while playing for his Italian Serie A side Udinese in the Europa League against Liverpool on Thursday.
Coach Kwesi Appiah has replaced him with another Italian-based midfielder Afriyie Acquah of Parma for the Lilongwe clash next week.
The Black Stars beat the Flames 2-0 in the first leg at the Accra Sports Stadium. A draw or a win is all that the four-time African champions need to qualify for South Africa 2013.