Goalkeeper Fatau Dauda and winger Solomon Asante have been handed their first Ghana starts for Tuesday's friendly against Liberia.
The two home-based players were named in coach Kwesi Appiah's starting line-up team for the game in Monrovia.
Dauda takes the place Adam Kwarasey while Asante gets the chance to impress with Andre Ayew on the bench.
Jerry Akaminko takes the place of Isaac Vorsah in central defence while Derek Boateng returns to the starting line-up.
The Black Stars play the Lone Star to mark Liberia's independence anniversary.
The match will kick off at 1600 GMT.
Starting line-up: Fatau Dauda, Samuel Inkoom, Razak Nuhu, John Boye, Jerry Akaminko, Anthony Annan, Solomon Asante, Derek Boateng, Asamoah Gyan, Kwadwo Asamoah, Christian Atsu.
Subs: Ernest Sowah, Rashid Sumaila, Isaac Coffie, Andre Ayew, Jordan Ayew, Abdul Majeed Waris, Richmond Boakye Yiadom.